Learn the difference between the original Omicron Corona strain, the Ghost strain and the New Cove Corona
What is the Omicron Ghost breed? And why did they give it that name? What is the difference between it and the original Omicron strain? And what about the New Cove breed? Here are the answers in this report.
What is the Stealth Omicron Subvariant?
It is a substrain of Corona Omicron, known as BA.2.
What is the difference between the Ghost Omicron bloodline and the original Omicron bloodline?
The original Omicron strain, known as BA1, is a highly contagious strain of the Corona virus, and is currently responsible for almost all HIV infections worldwide.
In addition to BA1 and BA.2, WHO lists two other subspecies under the Omicron umbrella, BA.529.1.1 (BA.1.1.529) and BA.3. (BA.3) All of these strains are closely related genetically, but each exhibit mutations that can change how they function.
In a tweet on Twitter last Friday, Trevor Bedford, a virologist at the Fred Hutchinson Cancer Center who monitors the evolution of the Corona virus, said that the “BA.2” strain is responsible for 82% of infections in Denmark, 9% in Britain and 8% in the United States, This is based on his analysis of the sequence data from the GISAID database and injury statistics from the Our World in Data project. (Our World in Data) at Oxford University, according to Reuters.
Why is the PA2 strain called the Ghost strain?
The PA1 version of the Omicron strain is relatively easier to track than previous strains; This is because PA1 does not have one of the 3 genes targeted by the PCR test.
PA2 does not have this missing target gene; Instead, scientists monitor it the way they monitored previous strains, including the Delta strain, by tracing the genetic maps of the genomes of viruses referred to public databases such as GISID.
Is PA2 more contagious?
Early reports suggest that PA2 may be more contagious than the already highly contagious PA1, but there is no evidence yet that it is likely to withstand vaccine protection.
Danish health officials estimate that the susceptibility of “PA2” to spread may be more than one and a half times that of “PA1”, based on preliminary data, although it probably does not cause more serious symptoms.
In England, a preliminary analysis of contact tracing from December 27, 2021 until January 11, 2022 – conducted by the Health Security Agency in the United Kingdom – indicates that the rate of transmission of infection at home is higher among contacts of people infected with the “PA.2” version, It is 13.4% compared to 10.3% in other Omicron strains.
The British agency did not find any evidence of a difference in the effectiveness of vaccines against these strains, according to the report issued on January 28.
However, a recent Danish study – published on Monday and reported by Reuters – concluded that the “BA.2” strain is more transmissible than the “PA1” strain.
The study – which analyzed data on coronavirus infections in more than 8,500 Danish families between last December and January – found that people infected with the “PA2″ strain were 33% more likely to transmit infection to other people compared to those infected with the strain. BA1”.
The PA1 strain represents more than 89%. One of the highly contagious Omicron infections of the Corona virus, but the new strain quickly became the dominant strain in Denmark, replacing “PA1” in the second week of last January.
“We concluded that PA2 is inherently more transmissible than PA1, and that it also possesses properties that enable it to evade the immune response, which reduces the protective effect of vaccines against infection,” the researchers said in the study.
The study was conducted by researchers at Statens Serum Institute, University of Copenhagen, Statistics Denmark and Technical University of Denmark.
Do those infected with the Omicron Ghost Race get protection from the original Omicron Bloodline?
An important question, says Dr. Egon Ozer, an infectious disease expert at Northwestern University’s Feinberg School of Medicine in Chicago, is whether people infected with the PA1 substrain get protection from the PA2 substrain.
He added that this question is of interest in Denmark, where some places have recorded many cases of “PA1” and increasing cases of “PA2”.
The good news, he said, is that vaccines and booster doses still “prevent people from hospitalization and death.”
What is NeoCoV?
Neo-CoV is a virus that differs from the PA1 sub-strain and the PA2 sub-strain. Neo-CoV has been detected in bats and is a close relative of the Middle East respiratory syndrome (MERS-CoV) virus.
The New Cove virus received media attention after a study about it conducted by Chinese scientists, mostly from Wuhan University, and published on the website “BioArchive(biorxiv) is in prepress, meaning it has not yet been accepted for publication in a peer-reviewed journal, nor has it been reviewed by other scholars.
The researchers said they unexpectedly found that New Cove and its relative PDF-2180-CoV can efficiently use some types of bat-specific angiotensin-converting enzyme 2 (ACE2) and, less preferably, for human angiotensin II to enter cells.
Can the New Cove virus infect humans?
The researchers didn’t say so, but said the main concern was whether the NewCoV and PDF-2180-CoV viruses could jump the species barrier and infect humans.
“Our study provided evidence that Neo-Cove like BDF-2180-Cove uses bat-specific angiotensin II for effective cellular entry,” the researchers said, adding that although the two viruses cannot efficiently use human angiotensin II, the study revealed that They can lead to a ‘site 510’ mutation in viruses enabling them to infect human cells that carry angiotensin II.”
The researchers said that this unexpected use of ACE from these two viruses (New Cove and PDF-2180-CoV) highlights the risks of a mutation that leads to the combination of two serious characteristics, namely the high mortality associated with MERS virus, and the high rate of transmission and infection associated with the virus. COVID-19.
Furthermore, the study shows that current COVID-19 vaccines are insufficient to protect humans from the possibility of infection caused by these viruses.